Tell your doctor right away if you have any serious side effects, including: abdominal pain, chest pain, irregular heartbeat (arrhythmias), pressure in the chest, severe headache and blurred vision (hypertension), problems with your dialysis access site (graft). However, since peoples bodies react so differently to drugs, they often have to change their stance on certain drugs. This is not a list of all drugs or health problems that interact with this medicine. Do not share your drugs with others and do not take anyone else's drugs. reactions at the site of the injection. Hypophosphatemia seems to mostly occur in people who are already at risk for low phosphorus levels. They can recommend appropriate treatment options. Feraheme also comes as a liquid thats given by IV infusion. Renal elimination is negligible. Serious side effects should be reported to a physician and/or PharmD for medical advice. And this type of reaction is possible even if you didnt have a reaction to your first dose of the drug. For more information about Injectafers approved uses, see the section Injectafer uses below. Does Venofer Vial interact with other drugs you are taking? *Patients are calculated based on an estimated annual cumulative dose. Note: The Food and Drug Administration (FDA) tracks side effects of drugs they have approved. Serious side effects, which are explained in more detail below in Side effect details, include: You may wonder how often certain side effects occur with this drug. Which tests can diagnose iron deficiency anemia? Many people using this medication do not have serious side effects. (A generic drug is an exact copy of the active drug in a brand-name medication.) VenAccess is a trademark of Vifor (International) Inc. Switzerland. This is a sudden response affecting the entire body, which sometimes happens to people who are allergic to peanuts or beestings. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. Details. This is not a complete list of possible side effects. To learn about other mild side effects, talk with your doctor or pharmacist, or see Injectafers package insert. In clinical studies, diarrhea was reported in less than 1% of people taking Injectafer. It will take about three weeks to feel the effects but your fatigue will disappear and you will feel like a new person. Remember that it is best to get your vitamins and minerals from food whenever possible. Before approving coverage for Injectafer, your insurance company may require you to get prior authorization. But you dont necessarily need to eat these foods unless your doctor tells you to do so. Amounts of iron ingested by the infant would be normal and are not expected to cause any adverse effects in breastfed infants. Diarrhea is a common side effect of most iron replacement products, which is the group of drugs that Injectafer belongs to. For example, if someone takes 100 mg of a drug, only half of it will be in the bloodstream in a couple ofhours. The way thatprescription drugsand evenover-the-countermedications interact with a body is influenced by manyfactors. Following an LSD trip, users may experience a sort of 'comedown.'. There are currently no generic forms of either drug. I got Venofer twice in the last few years and now my iron deficiency is worse than ever, first time my hemoglobin is down to 11,2. A variety of tests can diagnose iron deficiency anemia. Terminal half-life ranges from 7 to 12 hours. In clinical trials, serious allergic reactions occurred in 0.1% to 1.5% of people taking Injectafer. Your doctor will do laboratory tests to monitor your response. Call your doctor right away if you have chest pain, cough or the need to cough, dizziness, passing out, shortness of breath, sweating, or throat tightness. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction. Hypophosphatemia has been reported in people using Injectafer after the drug was released onto the market. Potentialside effectsthat are usually mild may include, but are not limitedto: Theseside effectsmay not impact life too much and may only be temporary. However, many people have no side effects or only have minor side effects. Phosphorus also helps your nerves function properly. * Sex and gender exist on spectrums. We cancelled my 5th because of the reaction. Keep all regular medical and laboratory appointments. Seriousside effectsshould be reported to a physician and/orPharmDfor medical advice. And this can affect how well those parts of your body are able to work. If these effects continue or worsen, tell your doctor. But in some people, Injectafer can cause symptoms of hypophosphatemia to occur. Your doctor may also recommend that you take iron supplements by mouth (if you havent tried these supplements in the past). Heres some detail on certain side effects this drug may cause. Maintain a well-balanced diet, and follow any dietary guidelines as directed by your doctor. In clinical trials,. The potential side effects of Daxxify are nearly identical to that of Botox bruising, headaches, and droopy eyelids with one big difference: They could last longer. With slow IV injection, the drug is given as a single, slow injection into your vein. For people weighing less than 50 kg, administer Injectafer in two doses of 15 mg/kg of body weight, at least 7 days apart. But its important to note that these studies werent designed to show whether Injectafer is safe to use during pregnancy. %PDF-1.3 Typical Injectafer doses for iron deficiency anemia (IDA) depends on your body weight. taste impairment. This gives a total cumulative dose of 1,500 mg of Injectafer. If you have iron deficiency anemia (IDA), consuming moderate amounts of alcohol may be safe, if your doctor tells you its OK. (With IDA, you have a low level of red blood cells thats caused by not having enough iron.). Do not flush down a toilet or pour down a drain unless you are told to do so. A healthcare provider will give you this injection. Discuss the risks and benefits with your doctor. Venofer (iron sucrose) injection, USP is an intravenous (IV) form of iron, which is a key ingredient for making new red blood cells. Understanding what thoseside effectsare can lead to a strategy to prevent them. If you have any of these health problems: Too much iron in your body or anemia from a cause other than low iron. There may be risks to the mother and fetus associated with untreated IDA in pregnancy. To help make sure that you dont miss appointments for your Injectafer doses, try setting an appointment reminder on your phone. Side effects from HRT depend on a number of factors: So we cant say for sure whether the drug is safe to use while youre pregnant. Best food forward: Are algae the future of sustainable nutrition? Its not currently available in generic form. The factors influencing how longside effectslast may not provide the answer most are looking for, but it does explain why some people cant take certain medications because theside effectsareunbearable. Injectafer contains the active drug ferric carboxymaltose. For reasons we dont fully understand, some peoples immune system gets over-activated when the drug enters their body. Talk with your doctor. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics(ACMG), an Associate of the American College of Preventive Medicine(ACPM), and a member of the National Society of Genetic Counselors(NSGC). Injectafer is approved to treat iron deficiency anemia (IDA) in certain adults with the condition. Its not known how common delayed allergic reaction might be in other people using Injectafer. Injectafer and Venofer can cause very similar side effects, but some different ones as well. Its FDA-approved to treat iron deficiency anemia (IDA) in adults. Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Keep all medications away from children and pets. People with IDA have low blood levels of hemoglobin. 1 0 obj But so far I feel better than before the infusion. Dizziness. However, since peoples bodies react so differently to drugs, they often have to change their stance on certaindrugs. Some products that may interact with this drug include: vitamin products, other iron-containing products. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. WebMD does not provide medical advice, diagnosis or treatment. All rights reserved. Injectafer and Feraheme have different approved uses, but theyre both used to treat IDA in certain adults. As with all medications, the cost of Injectafer can vary. Details. This is why family members often have the same issues with drugs as others in theirfamily. Its not known if Injectafer is safe to use during pregnancy. If youre interested in finding an alternative to Injectafer, talk with your doctor. If you have questions about using Injectafer in a child, talk with your doctor. Allergic reactions are most likely to occur within 30 minutes of receiving Venofer. Your doctor will determine the best dosage to fit your needs. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Venofer only for the indication prescribed. So theres no recommended pediatric dosage for Injectafer. Side effects: DayQuil can cause side effects such as drowsiness, dizziness, nausea, vomiting, and stomach upset. . These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Feraheme, or with both drugs (when taken individually). Iron infusions are given directly into a vein. Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when Venofer is injected. After the infusion, you can drive yourself home and return to your usual activities. An LSD comedown is when the mental and hallucinatory effects have worn . For this purpose, Injectafer is approved for use in adults who either: Venofer is also approved to treat IDA. Copyright 1996-2023 Cerner Multum, Inc. Common side effects of Venofer include: muscle cramps, nausea, vomiting, stomach pain, strange taste in the mouth or decreased sense of taste, diarrhea, constipation, headache, cough, sore throat, sinus pain, congestion, back pain, joint pain, dizziness, weakness, tired feeling, anxiety, ear pain, swelling of the arms/legs, or But its not known whether this poses any risk to a child whos breastfed. The Injectafer dosage your doctor prescribes will depend on your body weight. You should always consult your doctor or another healthcare professional before taking any medication. Nose or throat irritation. If you have iron deficiency anemia (IDA), there are certain foods you can eat that may help increase your iron levels. Venofer may cause significant hypotension (decreased blood pressure). Hes an expert in genetic testing, genetic analysis, andprecision medicine. pain or burning at the injection site. reese0809 1 yr. ago. These lists contain examples of serious side effects that can occur with Injectafer, with Venofer, or with both drugs (when taken individually). Venofer is given as an infusion into a vein. But for other people, their IDA returns after treatment with Injectafer. In the studies, peoples hemoglobin level was measured to check for improvement in their anemia. People who weigh less than 110 lb (about 50 kg) will receive two separate Injectafer doses of 15 mg/kg of body weight. These effects typically last between 7 and 11 hours. I actually was constipated after my 3rd but didn't think anything of it. You will need frequent medical tests to help your doctor determine how long to treat you with Venofer. Feraheme is also approved to treat IDA in adults who either didnt have improvement in their IDA or had side effects with iron treatment thats taken by mouth. Version: 7.01. If the underlying cause of your anemia isnt addressed, theres a chance your anemia could come back after Injectafer treatment. (A class of medications describes a group of drugs that work in the same way.). Below are examples of these side effects. What should I know regarding pregnancy, nursing and administering Venofer Vial to children or the elderly. On the other hand, some people may have a poor appetite that goes away when their anemia is treated. If administering via IV infusion, up to 750 mg of Injectafer should be diluted in no more than 250 mL of sterile 0.9% sodium chloride solution (NaCl). Limited data indicate that breastmilk iron is not increased after intravenous infusion of Venofer. This may be helped by giving the medication more slowly or at a lower dose. Suffering from somemedical conditionsput people at risk fordrugside effectsof medications for other health concerns. In clinical studies, people who took Injectafer still had iron in their system that was released by the drug 24 days after theyd gotten their injection. Last updated on Feb 20, 2023. Iron-refractory iron deficiency anemia (IRIDA) is a genetic form of anemia. Keep out of reach of children. Available for Android and iOS devices. Heart failure: Could a low sodium diet sometimes do more harm than good? Signs of high or low blood pressure like very bad headache or dizziness, passing out, or change in eyesight. If that happens, and your doctor thinks Injectafer is a good treatment option for you, you can receive another treatment course of the drug. (A class of medications describes a group of drugs that work in the same way.). Injectafer may not be right for you if you have certain medical conditions or other factors affecting your health. Most of these side effects may go away within a few days or a couple of weeks. signs of inflammation in the lining of your stomach - pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, fever. For example: Say you weigh 105 pounds (about 48 kilograms). Only 10 mg may be excreted by the body the next time it goes through the liver, and possibly only 5 mg the nextpass. For instance, those who are taking other medications or supplements as part of home remedies may continue to suffer from the ill effects of their new medication because they dontinteract. And these two doses need to be separated by at least 7 days. Youll receive doses of Injectafer from a healthcare professional at a medical facility. Side effects like nausea and low blood pressure are common with most iron infusions. But call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. treatment schedule in further detail. Symptoms of a severe allergic reaction can include: Because of the risk of allergic reaction with Injectafer, your healthcare professional will monitor you for at least 30 minutes after you get each dose of the drug. Injectafer contains the active drug ferric carboxymaltose. They can tell you about other medications that may work well for you. Before using iron sucrose, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Iron infusion side effects vary depending on which form is being used. fever. Since someallergic reactionscan belife-threatening, its essential to discuss any adverse events previously experienced with the prescribingphysician. You will need to talk about the benefits and risks to you and the baby. No, you dont need to follow a specific diet plan while youre using Injectafer unless your doctor recommends otherwise. The actual price youll pay depends on your insurance plan and any copays, your location, and the pharmacy you use. If youre concerned about weight changes while youre taking Injectafer, talk with your doctor. Do not use Injectafer in people with a history of hypersensitivity reactions to Injectafer or any components of the drug product. And the drug has also been studied in children with IDA who have inflammatory bowel disease (IBD). If you would like to report to the FDA a side effect youve had with Injectafer, you can do so through MedWatch. Venofer is used to treat iron deficiency anemia in people with kidney disease. Iron is an essential nutrient needed to maintain energy levels and keep you healthy. While the side effects that occur during treatment with these drugs are increasingly well-cataloged, the long-term side effects that may result from receiving these drugs are only beginning to be studied. While this may seem like it would be out of a persons body quickly, the rate of it being broken down is much slower afterward. It is given into a vein for a period of time. Most people will metabolize medication by half every time it circulates the body. Dilute Venofer in a maximum of 250 mL of 0.9% NaCl. Learn about the causes, symptoms, diagnosis, and treatment of this. Does Venofer Vial interact with other medications? Can diet help improve depression symptoms? This medication is given by injection into a vein as directed by your doctor. Notify your healthcare provider of all medical conditions and any medications, including supplements you are taking. This medicine is sometimes given slowly, and the infusion can take up to 2.5 hours to complete. These are not all of the side effects that may occur. ByDr. Undergoingcancer treatmentwithradiation therapyorchemotherapy drugsmay result inhair loss, which can be devastating to somepeople. Call your doctor for instructions if you miss an appointment for your Venofer injection. However, Injectafer has been studied for use in children with iron deficiency anemia (IDA). Before taking Injectafer, talk with your doctor about your health history. . (A medication class describes a group of drugs that work in the same way.). For some people, it may be OK to continue taking a multivitamin that contains iron. For example, some people with anemia have extreme fatigue (lack of energy), which can make it hard for them to exercise. With IDA, you have low hemoglobin levels. Injectafer can be exposed to temperatures between 59F to 86F (15C to 30F) for a short period of time. 2 Protocol for Intravenous iron sucrose - Venofer 2.1 Dosage The total cumulative dose of Venofer should be calculated using the table below. Injectafer isnt known to interact with any other medications, herbs, supplements, or foods. Fortunately, knowing how longside effectslast can help those suffering know what to donext. If you need to store Venofer at home, talk with your doctor, nurse, or pharmacist about how to store it. These side effects may include constipation and diarrhea. Venofer 100 mg iron/5 mL intravenous solution, Venofer 50 mg iron/2.5 mL intravenous solution, Venofer 200 mg iron/10 mL intravenous solution, Select a condition to view a list of medication options. Venofer is not for treating other forms of anemia not caused by iron deficiency. (And Injectafer is used to treat IDA.) Have blood work checked as you have been told by the doctor. The researchers found that compared with their hemoglobin level before the study: But the actual price youll pay for either drug depends on your insurance plan, your location, and the pharmacy you use. It is very important that your doctor check you closely while you are receiving this medicine. This website is intended for use by US patients. I had my first infusion of 1gm 10 days ago. Some people only need one treatment course of Injectafer. Iron sucrose can also be mixed in a saline solution and given through an IV over a longer time. So the goal of anemia treatment is to increase your hemoglobin level back to a value thats within a normal range. other treatments you receive, you will need to go back for several treatments with Venofer. Allergic reaction As with most drugs, some people can have an allergic reaction after taking Injectafer. Here we look at how Injectafer and Venofer are alike and different. Its possible to get rid of or reduce the severity ofside effects. Venofer treatment may be repeated if iron deficiency reoccurs. The next time the doctor prescribesprescription medication, ask aboutcommonside effectsand if they are known to last a short or longtime. Call your doctor for medical advice about side effects. Learn about uses, cost, how it works, and more. If youre wondering how longside effectslast, youll be happy to know they can last just a few hours. Those going through thismedical conditionshould speak to theircare teamfor support andguidance. Boxed warnings alert doctors and patients about drug effects that may be dangerous. These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Venofer, or with both drugs (when taken individually). Do not start, stop, or change the dose of any drug without checking with your doctor. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. (For more information on Venofer, see the Injectafer vs. Venofer section above). Notify your healthcare provider of any irritation at the injection site. Click below for effective ways to alleviate the discomfort felt fromside effects and learn how to get a free Medication and Drug Reaction DNAReport. These lists dont include all possible side effects. In this study, researchers compared Feraheme treatment with that of ferric carboxymaltose (the active drug in Injectafer). Mental healthdisorders like depression may requireantidepressantsto treat. It depends. Weight changes may be due to symptoms of anemia improving. FG Trade/E+ sia Getty Images In one study, people were given either Injectafer or an iron replacement drug called Venofer. Venofer pregnancy and breastfeeding warnings. This medication is given by injection into a vein as directed by your doctor. fever. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Your body then uses the iron from Injectafer to make hemoglobin and new RBCs. Back pain. However, not treating iron deficiency anemia during pregnancy may cause complications such as premature birth or low birth weight. * Feraheme has a boxed warning for this side effect. However, there has been a report of delayed allergic reaction in someone receiving a second dose of Injectafer. In this group, after 35 days of treatment: In clinical studies, Injectafer was effective in treating IDA in adults with CKD who didnt require dialysis. If you have symptoms of a low phosphorus level, call your doctor. Patients should induce vomiting or evacuate the stomach by lavage during Venofer overdoasge. Not all possible drug interactions are listed here. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine. Many people using this medication do not have serious side effects.Severe dizziness or fainting (hypotension) may occur while you are receiving IV iron. (Hemoglobin is a protein thats found in your red blood cells.). endobj Before taking Injectafer, be sure to tell your doctor or pharmacist about any medications you take, including any over-the-counter vitamins or supplements. People in the study received treatment with either Injectafer or Venofer. You may wonder how Injectafer compares with other medications that are prescribed for similar uses. If either is present, do not use the liquid. Check with your pharmacist. A very serious allergic reaction to this drug is unlikely, but get medical help right away if it occurs. How long does iron infusion stay in your system? Potential side effects that are usually mild may include, but are not limited to: Headache Nausea Dry Mouth Stomachache Dizziness Diarrhea Constipation These side effects may not impact life too much and may only be temporary. Hypophosphatemia risk appears to be substantially lower with other IV iron formulations. % One study of just under 5000 HRT users found that 43% were affected. Theseeffects of medicine on thebodycan also lead to medication non-compliance and worsening of themedical conditionthey are meant to treat. To make sure Venofer injection is safe for you, tell your doctor if you have: hemochromatosis or iron overload (the buildup of excess iron). With a delayed reaction, your body reacts to a drug that youve been exposed to in the past without having a reaction. Venofer can be given as a maximum of 200mg not more than 3 times per week; doses must be 24 hours apart. Then your body uses that iron to make hemoglobin and RBCs. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about side effects, call your doctor. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. This website is intended for use by US healthcare professionals only. Severeside effectsmay end up causing a lot of disruption in a persons life. You may report side effects to Health Canada at 1-866-234-2345. Common MRI side effects include dizziness, anxiety, headache, nausea, hearing loud noises, and feeling chilled or hot in the MRI scanner. What to Expect When You Get Your Whole Genome Sequenced, DNA Data Can Help You Understand Ehlers-Danlos Syndrome (EDS). Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: These are not all of the side effects that may occur. Talk with the doctor. For instance, someone with lowblood pressuremay receive a medication to prevent migraines that lowersblood pressure, this may causeseriousside effects. If you miss an appointment for your Injectafer dose, youll need to call your doctors office. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. If you have questions about the blood tests youll need to have done to monitor your anemia, talk with your doctor. With anemia, you have a low level of red blood cells (RBCs) in your body. Or your doctor may recommend that you change your eating habits to include more iron in your diet. However, diarrhea it isnt very common in people using Injectafer. In the study, peoples hemoglobin level was measured to check for improvement in their anemia. Low iron saturation, or iron deficiency, has various possible causes. Dr. Brandon ColbyMDis a US physician specializingin the personalized prevention of disease through the use of genomic technologies. You may report side effects to the FDA at 1-800-332-1088. Instead, youll start by receiving just one treatment course of Injectafer. Pain, swelling, or redness at the injection site may occur. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. I used to get a different type but my . In some cases, they may even recommend that you use a drug other than Injectafer to treat your anemia. Its possible that after getting two doses of Injectafer, your anemia may go away completely. Someside effectsare temporary or last as long as the person continues takingprescription medicine. If you are allergic to Venofer; any part of this medicine; or any other drugs, foods, or substances. If this happens, you may need to get another treatment course of Injectafer, if your doctor recommends it for you. Tell your doctor about the allergy and what signs you had. Here's some detail on certain side effects this drug may cause. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. I hope you found answers and are feeling better now. Iron sucrose injection has a molecular weight of approximately 34,000 - 60,000 daltons and a proposed structural formula: With IDA, you have low hemoglobin levels. For some people, after receiving one treatment course (two doses) of Injectafer, their IDA is resolved. Symptoms include shock, dangerously low blood pressure, loss of consciousness, and/or collapse. 3 0 obj A shortage of iron can cause health problems. chills difficulty with moving ear congestion or pain flushed, dry skin fruit-like breath odor increased hunger or thirst increased urination lack or loss of strength pain or redness at the injection site pale skin at the injection site runny nose, sneezing sore throat unexplained weight loss Rare Burning, dry, or itching eyes It can be given as a slow injection over 2 to 5 minutes or as an infusion. Venofer (iron sucrose) can also be mixed in a saline solution and given through an IV over a longer time. Venofer and the Venofer logo are registered trademarks of Vifor (International) Inc., Switzerland.
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